Indeed, two recent studies shown that anchorage-dependent growth of some human breast tumor cell lines is definitely impaired by cyclopamine, a potent hedgehog signaling antagonist focusing on the (SMO) protein. and ER-negative tumorigenic breast tumor cells at elevated … Continue reading Indeed, two recent studies shown that anchorage-dependent growth of some human breast tumor cell lines is definitely impaired by cyclopamine, a potent hedgehog signaling antagonist focusing on the (SMO) protein